Article
Loss of p27KIP1 expression in fully-staged node-negative breast cancer: association with lack of hormone receptors in T1a/b, but not T1c infiltrative ductal carcinoma.
Anticancer research - 1 Dec 2011
Mirchandani Deepu, Roses Daniel F, Inghirami Giorgio, Zeleniuch-Jacquotte Anne, Cangiarella Joan, Guth Amber, Safyan Rachael Ann, Formenti Silvia C, Pagano Michele, Muggia Franco
Abstract excerpt
UNLABELLED: Nuclear expression of the cell cycle inhibitor p27(KIP1) is reduced in a variety of human malignancies, including breast cancer. Loss of nuclear p27(KIP1) during tumor progression, documented by immunohistochemistry (IHC), has been studied for its potential prognostic implication. We examined by IHC the association between nuclear p27(KIP1) expression and hormone receptor status in T1N0M0 breast...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.