Article
Cell cycle proteins do not predict outcome in grade I infiltrating ductal carcinoma of the breast.
International journal of cancer - 20 Jan 2000
Leong A C, Hanby A M, Potts H W, Tan D S, Skilton D, Ryder K, Harris W H, Liebmann R D, Barnes D M, Gillett C E
Abstract excerpt
Infiltrating ductal mammary carcinomas are histologically graded according to their extent of differentiation. Well-differentiated, grade I, tumours have low proliferative activity, usually form tubules and exhibit little nuclear pleomorphism. Despite an apparently reassuring morphology, 10-15% of grade I ductal carcinomas metastasize, albeit after a prolonged period. Recent evidence supports the view that...
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