Article
XPD and hOGG1 gene polymorphisms in reperfusion oxidative stress.
Genetics and molecular research : GMR - 19 Dec 2011
Isbir O, Görmüş U, Ergen H A, Cakmakoğlu B, Kahraman O T, Baykan N
Abstract excerpt
Knee replacement surgery is an ischemia/reperfusion model, as it uses tourniquet applied to the knee area to stop the blood flow during the operation. Fifty patients that were undergoing elective arthroscopic knee surgery were included in our study. Human 8-oxoguanine glycosylase 1 (hOGG1) is an enzyme to repair specific DNA lesions and a good marker of hydroxyl radical damage to DNA. XPD is another DNA...
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