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Effect of Human OGG1 1245C→G Gene Polymorphism on 8-Hydroxy-2′-Deoxyguanosine Levels of Leukocyte DNA among Patients Undergoing Chronic Hemodialysis

1 Nov 2001

Abstract excerpt

The effects of the human OGG1 gene (hOGG1) 1245C-->G polymorphism on the 8-hydroxy-2'-deoxyguanosine (8-OHdG) contents of peripheral leukocyte DNA were investigated among chronic hemodialysis patients. First, the hOGG1 1245C-->G transversion was assessed, by using a PCR-restriction fragment length polymorphism method, among 210 hemodialysis patients and 156 healthy individuals. Second, the 8-OHdG contents in...

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PMID: 11675410
DOI: 10.1681/asn.v12112338

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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