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Article

Impaired alternative macrophage differentiation of peripheral blood mononuclear cells from obese subjects.

Diabetes & vascular disease research - 1 Jul 2012

Bories Gael, Caiazzo Robert, Derudas Bruno, Copin Corinne, Raverdy Violeta, Pigeyre Marie, Pattou Francois, Staels Bart, Chinetti-Gbaguidi Giulia

Abstract excerpt

Visceral obesity is a chronic, low-grade inflammatory disease that predisposes people to the metabolic syndrome, type 2 diabetes and its cardiovascular complications. Adipose tissue is not a passive storehouse for fat, but an endocrine organ synthesizing and releasing a variety of bioactive molecules, some of which are produced by infiltrated immune-inflammatory cells including macrophages. Two different...

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Share to Adipose Tissue
Share to Cell Differentiation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

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Share to Leukocytes, Mononuclear

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Source

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Identifiers

PMID: 22192929
DOI: 10.1177/1479164111430242
PMCID: PMC3655375

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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