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Article

Human adipose tissue macrophages are enhanced but changed to an anti-inflammatory profile in obesity.

Journal of immunology research - 1 Jan 2014

Fjeldborg Karen, Pedersen Steen B, Møller Holger J, Christiansen Tore, Bennetzen Marianne, Richelsen Bjørn

Abstract excerpt

OBJECTIVE: Adipose tissue (AT) macrophages are increased in obesity and associated with low grade inflammation. We aimed to characterize the phenotype of AT macrophages in humans in relation to obesity and insulin resistance. DESIGN: Gene-expression levels of general macrophage markers (CD68 and CD14), proinflammatory markers/M1 (TNF-α, MCP-1, and IL-6), and anti-inflammatory markers/M2 (CD163, CD206, and IL-10)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24741586
DOI: 10.1155/2014/309548
PMCID: PMC3987875

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TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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