Article
A decade of progress in adipose tissue macrophage biology.
Immunological reviews - 1 Nov 2014
Hill Andrea A, Reid Bolus W, Hasty Alyssa H
Abstract excerpt
One decade has passed since seminal publications described macrophage infiltration into adipose tissue (AT) as a key contributor to inflammation and obesity-related insulin resistance. Currently, a PubMed search for 'adipose tissue inflammation' reveals over 3500 entries since these original reports. We now know that resident macrophages in lean AT are alternatively activated, M2-like, and play a role in AT...
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