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Article

Alternative Macrophage Activation and Metabolism

24 Jan 2011

Abstract excerpt

Obesity and its attendant metabolic disorders represent the great public health challenge of our time. Recent evidence suggests that onset of inflammation in metabolic tissues pathogenically links obesity to insulin resistance and type 2 diabetes. In this review, we briefly summarize the extant literature, paying special attention to the central role of the tissue-associated macrophage in the initiation of...

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PMID: 21034223
DOI: 10.1146/annurev-pathol-011110-130138

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