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Article

Type I interferon pathway in adult and juvenile dermatomyositis

1 Jan 2011

Abstract excerpt

Gene expression profiling and protein studies of the type I interferon pathway have revealed important insights into the disease process in adult and juvenile dermatomyositis. The most prominent and consistent feature has been a characteristic whole blood gene signature indicating upregulation of the type I interferon pathway. Upregulation of the type I interferon protein signature has added additional markers of...

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PMID: 22192711
DOI: 10.1186/ar3531

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