Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene expression profiling in DQA1*0501+ children with untreated dermatomyositis: a novel model of pathogenesis.

Journal of immunology (Baltimore, Md. : 1950) - 15 Apr 2002

Tezak Zivana, Hoffman Eric P, Lutz Jennica L, Fedczyna Tamara O, Stephan Dietrich, Bremer Eric G, Krasnoselska-Riz Irina, Kumar Ajit, Pachman Lauren M

Abstract excerpt

Juvenile dermatomyositis (JDM), the most common pediatric inflammatory myopathy, is a systemic vasculopathy affecting young children. Epidemiology studies documenting an antecedent illness in the 3 mo before the first definite symptom (rash and/or weakness) of JDM are supported by immunologic data that suggest that the disease pathophysiology is Ag driven. The purpose of this study was to compare the gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cyclin-Dependent Kinase Inhibitor p21
Share to Cyclins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dermatomyositis

Share to Gene Expression Regulation, Viral

Share to HLA-DQ alpha-Chains

Share to HLA-DQ Antigens

Share to Muscular Dystrophy, Duchenne

Share to Thrombospondins

Source

Identifiers

PMID: 11937576
DOI: 10.4049/jimmunol.168.8.4154

Genes

TAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene expression profiling in DQA1*0501+ children with untreated dermatomyositis: a novel model of pathogenesis.PMID 11937576Read ↗

Transcriptomes of peripheral blood mononuclear cells from juvenile dermatomyositis patients show elevated inflammation even when clinically inactiveSemantic proximity Read ↗

Type I interferon pathway in adult and juvenile dermatomyositisSemantic proximity Read ↗

Immunopathogenesis of juvenile dermatomyositis.Semantic proximity Read ↗

Expression of interferon-regulated genes in juvenile dermatomyositis versus Mendelian autoinflammatory interferonopathiesSemantic proximity Read ↗

Gene Expression Profiling in Blood and Affected Muscle Tissues Reveals Differential Activation Pathways in Patients with New-onset Juvenile and Adult DermatomyositisSemantic proximity Read ↗

Update on juvenile dermatomyositis: new advances in understanding its etiopathogenesis.Semantic proximity Read ↗

Multi-modal single-cell sequencing identifies cellular immunophenotypes associated with juvenile dermatomyositis disease activitySemantic proximity Read ↗

Juvenile dermatomyositis: immunogenetics, pathophysiology, and disease expression.Semantic proximity Read ↗

Comprehensive analysis reveals potential molecular targets in Juvenile DermatomyositisSemantic proximity Read ↗

Multi-Modal Single-Cell Sequencing Identifies Cellular Immunophenotypes Associated With Juvenile Dermatomyositis Disease ActivitySemantic proximity Read ↗

Dysregulated dsRNA sensor signaling and viral infection during onset of pediatric autoimmune interferonopathySemantic proximity Read ↗

Juvenile dermatomyositis: the association of the TNF alpha-308A allele and disease chronicity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.