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Article

Type I interferon–inducible gene expression in blood is present and reflects disease activity in dermatomyositis and polymyositis

29 Oct 2007

Abstract excerpt

OBJECTIVE: To apply gene expression profiling to the study of peripheral blood mononuclear cells from patients with inflammatory myopathies, in order to provide insight into disease pathogenesis and identify potential biomarkers associated with disease activity. METHODS: We used Affymetrix whole-genome microarrays to measure the expression of approximately 38,500 genes in 65 blood and 15 muscle samples from 44...

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PMID: 17968926
DOI: 10.1002/art.22928

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