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Article

Assessment of Type I Interferon Signaling in Pediatric Inflammatory Disease.

Journal of clinical immunology - 1 Feb 2017

Rice Gillian I, Melki Isabelle, Frémond Marie-Louise, Briggs Tracy A, Rodero Mathieu P, Kitabayashi Naoki, Oojageer Anthony, Bader-Meunier Brigitte, Belot Alexandre, Bodemer Christine, Quartier Pierre, Crow Yanick J

Abstract excerpt

PURPOSE: Increased type I interferon is considered relevant to the pathology of a number of monogenic and complex disorders spanning pediatric rheumatology, neurology, and dermatology. However, no test exists in routine clinical practice to identify enhanced interferon signaling, thus limiting the ability to diagnose and monitor treatment of these diseases. Here, we set out to investigate the use of an assay...

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Identifiers

PMID: 27943079
DOI: 10.1007/s10875-016-0359-1
PMCID: PMC5325846

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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