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Article

SySAP: a system-level predictor of deleterious single amino acid polymorphisms.

Protein & cell - 1 Jan 2012

Huang Tao, Wang Chuan, Zhang Guoqing, Xie Lu, Li Yixue

Abstract excerpt

Single amino acid polymorphisms (SAPs), also known as non-synonymous single nucleotide polymorphisms (nsSNPs), are responsible for most of human genetic diseases. Discriminate the deleterious SAPs from neutral ones can help identify the disease genes and understand the mechanism of diseases. In this work, a method of deleterious SAP prediction at system level was established. Unlike most existing methods, our...

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Identifiers

PMID: 22183811
DOI: 10.1007/s13238-011-1130-2
PMCID: PMC4875213

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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