Article
In silico prediction of deleterious single amino acid polymorphisms from amino acid sequence.
Journal of computational chemistry - 1 May 2011
Li Shuyan, Xi Lili, Li Jiazhong, Wang Chengqi, Lei Beilei, Shen Yulin, Liu Huanxiang, Yao Xiaojun, Li Biao
Abstract excerpt
Molecular cause of human disease retains as one of the most attractive scientific research targets for decades. An effective approach toward this topic is analysis and identification of disease-related amino acid polymorphisms. In this work, we developed a concise and promising deleterious amino acid polymorphism identification method SeqSubPred based on 44 features solely extracted from protein sequence....
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