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Article

Increased FGFR1 copy number in lung squamous cell carcinomas

15 Dec 2011

Abstract excerpt

The basic fibroblast growth factor (bFGF), via activation of its receptor, FGFR1, has been postulated to be an important inducer of host stromal response and angiogenesis. More recently, FGFR1 amplifications were investigated using large-scale single nucleotide polymorphism arrays in lung cancer. We hypothesized that FGFR1 overexpression may be correlated with the clinicopathological features of lung cancers. The...

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PMID: 22179561
DOI: 10.3892/mmr.2011.715

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