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Inhibitor-Sensitive FGFR1 Amplification in Human Non-Small Cell Lung Cancer

7 Jun 2011

Abstract excerpt

BACKGROUND: Squamous cell lung carcinomas account for approximately 25% of new lung carcinoma cases and 40,000 deaths per year in the United States. Although there are multiple genomically targeted therapies for lung adenocarcinoma, none has yet been reported in squamous cell lung carcinoma. METHODOLOGY/PRINCIPAL FINDINGS: Using SNP array analysis, we found that a region of chromosome segment 8p11-12 containing...

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PMID: 21666749
DOI: 10.1371/journal.pone.0020351

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