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Article

The anabolic/androgenic steroid nandrolone exacerbates gene expression modifications induced by mutant SOD1 in muscles of mice models of amyotrophic lateral sclerosis.

Pharmacological research - 1 Feb 2012

Galbiati Mariarita, Onesto Elisa, Zito Arianna, Crippa Valeria, Rusmini Paola, Mariotti Raffaella, Bentivoglio Marina, Bendotti Caterina, Poletti Angelo

Abstract excerpt

Anabolic/androgenic steroids (AAS) are drugs that enhance muscle mass, and are often illegally utilized in athletes to improve their performances. Recent data suggest that the increased risk for amyotrophic lateral sclerosis (ALS) in male soccer and football players could be linked to AAS abuse. ALS is a motor neuron disease mainly occurring in sporadic (sALS) forms, but some familial forms (fALS) exist and have...

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Identifiers

PMID: 22178654
DOI: 10.1016/j.phrs.2011.12.001
PMCID: PMC3272141

Genes

SOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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