Article
Somitogenesis in the anole lizard and alligator reveals evolutionary convergence and divergence in the amniote segmentation clock.
Developmental biology - 1 Mar 2012
Eckalbar Walter L, Lasku Eris, Infante Carlos R, Elsey Ruth M, Markov Glenn J, Allen April N, Corneveaux Jason J, Losos Jonathan B, DeNardo Dale F, Huentelman Matthew J, Wilson-Rawls Jeanne, Rawls Alan, Kusumi Kenro
Abstract excerpt
The axial skeleton is a defining feature of vertebrates and is patterned during somitogenesis. Cyclically expressed members of the notch and other signaling pathways, described as the 'segmentation clock', regulate the formation of somite boundaries. Comparisons among vertebrate model systems have revealed fundamental shifts in the regulation of expression among critical genes in the notch pathway. However,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
