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Article

Regulation of human formyl peptide receptor 1 synthesis: role of single nucleotide polymorphisms, transcription factors, and inflammatory mediators.

PloS one - 1 Jan 2011

Miettinen Heini M

Abstract excerpt

The gene encoding the human formyl peptide receptor 1 (FPR1) is heterogeneous, containing numerous single nucleotide polymorphisms (SNPs). Here, we examine the effect of these SNPs on gene transcription and protein translation. We also identify gene promoter sequences and putative FPR1 transcription factors. To test the effect of codon bias and codon pair bias on FPR1 expression, four FPR1 genetic variants were...

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Identifiers

PMID: 22174875
DOI: 10.1371/journal.pone.0028712
PMCID: PMC3235167

Genes

FPR1

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