Article
Functional polymorphisms of the FPR1 gene and aggressive periodontitis in Japanese.
Biochemical and biophysical research communications - 7 Dec 2007
Gunji Tomohiko, Onouchi Yoshihiro, Nagasawa Toshiyuki, Katagiri Sayaka, Watanabe Hisashi, Kobayashi Hiroaki, Arakawa Shinichi, Noguchi Kazuyuki, Hata Akira, Izumi Yuichi, Ishikawa Isao
Abstract excerpt
Aggressive periodontitis (AgP), a severe and early onset type of periodontitis, is thought to be subject to significant genetic background effects. Formyl peptide receptor 1 (FPR1) is a gene strongly implicated in AgP. To determine whether variations in this gene are associated with AgP, we performed an association study with 49 AgP patients and 373 controls using 30 variations identified by sequencing the...
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