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Article

Impact of prothrombin and factor V Leiden mutations on the progression of fibrosis in patients with chronic hepatitis C.

PloS one - 1 Jan 2022

Naguib Mary, Abdel-Razek Wael, Estaphan Suzanne, Abdelsameea Eman, Abdel-Samiee Mohamed, Shafik Nevine F

Abstract excerpt

BACKGROUND: The role of thrombotic factors in the pathogenesis and progression of liver fibrosis remains obscure. We aimed to study the relationship between prothrombin G20210A (PT20210) and factor V Leiden (FVL) mutations and the progression of fibrosis and liver function in chronic HCV patients. METHODS: The study included 100 subjects, 88 patients with HCV-related cirrhosis (compensated: 38, decompensated:...

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Identifiers

PMID: 36355755
DOI: 10.1371/journal.pone.0276592
PMCID: PMC9648710

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