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Article

Prothrombotic genetic risk factors are associated with an increased risk of liver fibrosis in the general population: The Rotterdam Study.

Journal of hepatology - 1 Dec 2015

Plompen Elisabeth P C, Darwish Murad Sarwa, Hansen Bettina E, Loth Daan W, Schouten Jeoffrey N L, Taimr Pavel, Hofman Albert, Uitterlinden André G, Stricker Bruno H, Janssen Harry L A, Leebeek Frank W G

Abstract excerpt

BACKGROUND & AIMS: The coagulation system is known to be involved in fibrogenesis in patients with liver disease. We investigated whether common genetic prothrombotic risk factors are associated with an increased risk of fibrosis in the general population. METHODS: This investigation was part of the Rotterdam Study, an ongoing, population-based cohort study. Liver stiffness (LS) was measured using transient...

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PMID: 26226452
DOI: 10.1016/j.jhep.2015.07.026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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