Article
The impact of inherited prothrombotic risk factors on individuals chronically infected with hepatitis C virus from a single source.
Journal of viral hepatitis - 1 Apr 2007
Goulding C, O'Brien C, Egan H, Hegarty J E, McDonald G, O'Farrelly C, White B, Kelleher D, Norris S
Abstract excerpt
Intrahepatic thrombotic events have been postulated to play a key role in the pathogenesis of hepatic fibrosis. Genetic and acquired thrombotic risk factors may therefore contribute to the varying rates of fibrosis progression observed in patients with chronic hepatitis C virus (HCV) infection. The aim of this study was to assess the impact of inherited mutations in factor V and factor II (prothrombin) on hepatic...
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