Article
Human aging in the post-GWAS era: further insights reveal potential regulatory variants.
Biogerontology - 1 Aug 2015
Haider Syed Aleem, Faisal Muhammad
Abstract excerpt
Human aging involves a gradual decrease in cellular integrity that contributes to multiple complex disorders such as neurodegenerative disorders, cancer, diabetes, and cardiovascular diseases. Genome-wide association studies (GWAS) play a key role in discovering genetic variations that may contribute towards disease vulnerability. However, mostly disease-associated SNPs lie within non-coding part of the genome;...
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