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Kisspeptin expression in guinea pig hypothalamus: Effects of 17β‐estradiol

15 Dec 2011

Abstract excerpt

Kisspeptin is essential for reproductive functions in humans. As a model for the human we have used the female guinea pig, which has a long ovulatory cycle similar to that of primates. Initially, we cloned a guinea pig kisspeptin cDNA sequence and subsequently explored the distribution and 17β-estradiol (E2) regulation of kisspeptin mRNA (Kiss1) and protein (kisspeptin) by using in situ hybridization, real-time...

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PMID: 22173890
DOI: 10.1002/cne.23032

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