Overview of the impact of kisspeptin on reproductive function.

doi:10.1016/j.ando.2012.07.680

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Article

Overview of the impact of kisspeptin on reproductive function.

Annales d'endocrinologie - 1 Nov 2012

Sonigo Charlotte, Binart Nadine

Abstract excerpt

Since 2003, kisspeptin and its receptor (KISS1R, also called GPR54) are recognized as major actors of the gonadotrope axis. Mutations of genes encoding the peptide or the receptor have been identified in patients with precocious puberty or hypogonadotropic hypogonadism. They are strong stimulators of GnRH neurons and are involved in various mechanisms regulating gonadotrope axis as puberty induction or positive...

Topics

Animals
Arcuate Nucleus of Hypothalamus
Female
Gonadotropin-Releasing Hormone
Gonadotropins
Humans
Hypogonadism
Kisspeptins
Male
Mice
Mice, Knockout
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neurons

Paraventricular Hypothalamic Nucleus

Placenta

Pregnancy

Puberty

Puberty, Precocious

Source

Open in PubMed

Identifiers

PMID: 23000239
DOI: 10.1016/j.ando.2012.07.680

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