Article
Discovery and Evolutionary History of Gonadotrophin‐Inhibitory Hormone and Kisspeptin: New Key Neuropeptides Controlling Reproduction
6 May 2010
Abstract excerpt
Gonadotrophin-releasing hormone (GnRH) is the primary hypothalamic factor responsible for the control of gonadotrophin secretion in vertebrates. However, within the last decade, two other hypothalamic neuropeptides have been found to play key roles in the control of reproductive functions: gonadotrophin-inhibitory hormone (GnIH) and kisspeptin. In 2000, we discovered GnIH in the quail hypothalamus. GnIH inhibits...
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