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Article

RASSF1A hypermethylation is associated with aflatoxin B1 and polycyclic aromatic hydrocarbon exposure in hepatocellular carcinoma.

Hepato-gastroenterology - 1 Sept 2012

Feng Ying, Xue Wan-Jiang, Li Peng, Sha Zhen-Yu, Huang Hua, Rui Li, Li Hou-Xiang, Mao Qin-Sheng

Abstract excerpt

BACKGROUND/AIMS: RASSF1A hypermethylation is frequently observed in hepatocellular carcinomas (HCC). But the possible related risk factors and prognosis evaluation for this epigenetic alteration are still unknown. METHODOLOGY: Methylation status, mRNA and protein expression of RASSF1A, aflatoxin B1 (AFB1) and polycyclic aromatic hydrocarbon (PAH)-DNA adducts, were examined in 103 cases of HCC. RESULTS: The...

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PMID: 22172412
DOI: 10.5754/hge11731

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PAH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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