Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alterations of DNA methylation and histone modifications contribute to gene silencing in hepatocellular carcinomas

20 Jun 2007

Abstract excerpt

AIM: The aim of the present study was to examine DNA methylation and histone modification changes in hepatocellular carcinomas (HCC). METHODS: DNA methylation in the P16, RASSF1a, progesterone receptor (PGR) and estrogen receptor alpha (ERalpha) promoters was determined by quantitative bisulfite-pyrosequencing technique in HCC patients. Histone H3-lysine (K) 4, H3-K9 and H3-K27 modifications in all these four...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Epigenetics and DNA Methylation
Share to Histone Deacetylase Inhibitors Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17584191
DOI: 10.1111/j.1872-034x.2007.00141.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alterations of DNA methylation and histone modifications contribute to gene silencing in hepatocellular carcinomasPMID 17584191Read ↗

Role of epigenetic aberrations in the development and progression of human hepatocellular carcinoma.Semantic proximity Read ↗

Advances in Epigenetics of Hepatocellular CarcinomaSemantic proximity Read ↗

DNA methylation and gene expression profiling highlight retinol metabolism's vital role in Hepatocellular carcinoma developmentSemantic proximity Read ↗

Sex and Race-Related DNA Methylation Changes in Hepatocellular Carcinoma.Semantic proximity Read ↗

Comprehensive review and updated analysis of DNA methylation in hepatocellular carcinoma: From basic research to clinical applicationSemantic proximity Read ↗

Epigenetics in hepatocellular carcinoma: an update and future therapy perspectives.Semantic proximity Read ↗

Variable DNA methylation patterns associated with progression of disease in hepatocellular carcinomasSemantic proximity Read ↗

Clinical implications of DNA methylation in hepatocellular carcinoma.Semantic proximity Read ↗

Epigenetic modification and risk of Hepatocellular carcinoma in high incidence region of Northeast IndiaSemantic proximity Read ↗

Interplay of Genetic and Epigenetic Alterations in Hepatocellular CarcinomaSemantic proximity Read ↗

Identification by TCGA database search of five genes that are aberrantly expressed and involved in hepatocellular carcinoma potentially via DNA methylation changesSemantic proximity Read ↗

DNA methylation and gene expression profiles show novel regulatory pathways in hepatocellular carcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.