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Article

Detection of single nucleotide polymorphisms within a sequence of a gene associated with prostate cancer using a fluorophore-tagged DNA probe.

Bioorganic & medicinal chemistry letters - 1 Jan 2012

Zhao Zheng-Yun, San Marie, Duprey Jean-Louis H A, Arrand John R, Vyle Joseph S, Tucker James H R

Abstract excerpt

Single nucleotide polymorphisms within a sequence of a gene associated with prostate cancer were identified using oligodeoxynucleotide probe sequences bearing internal anthracene fluorophores proximal to the SNP site. Depending upon the nature of the synthesised target sequences, probe-target duplex formation could lead to enhanced or attenuated fluorescence emission from the anthracene, enabling detection of a...

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PMID: 22169264
DOI: 10.1016/j.bmcl.2011.11.053

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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