Article
Detection of a single DNA base-pair mismatch using an anthracene-tagged fluorescent probe.
Chemical communications (Cambridge, England) - 28 Dec 2006
Moran Nina, Bassani Dario M, Desvergne Jean-Pierre, Keiper Sonja, Lowden Philip A S, Vyle Joseph S, Tucker James H R
Abstract excerpt
A novel anthracene-tagged oligonucleotide can discriminate between a fully-matched DNA target sequence and one with a single mismatching base-pair through a remarkable difference in fluorescence emission intensity upon duplex formation.
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