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Article

AcrB trimer stability and efflux activity, insight from mutagenesis studies.

PloS one - 1 Jan 2011

Yu Linliang, Lu Wei, Wei Yinan

Abstract excerpt

The multidrug transporter AcrB in Escherichia coli exists and functions as a homo-trimer. The assembly process of obligate membrane protein oligomers, including AcrB, remains poorly understood. In a previous study, we have shown that individual AcrB subunit is capable of folding independently, suggesting that trimerization of AcrB follows a three-stage pathway in which monomers first fold, and then assemble. Here...

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Identifiers

PMID: 22163011
DOI: 10.1371/journal.pone.0028390
PMCID: PMC3230630

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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