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Article

A Korean Parkinson's disease family with the LRRK2 p.Tyr1699Cys mutation showing clinical heterogeneity.

Movement disorders : official journal of the Movement Disorder Society - 1 Feb 2012

Kim Ji Sun, Cho Jin Whan, Shin Hyeeun, Lee Won Yong, Ki Chang-Seok, Cho Ah Ra, Kim Hee-Tae

Abstract excerpt

BACKGROUND: Although leucine-rich repeat kinase 2 (LRRK2) is the gene most commonly linked to autosomal dominant inherited Parkinson's disease (PD), there have been few reports in Asia, probably because of population-specific differences in allele frequencies. METHODS: We identified a large Korean PD family with the p.Tyr1699Cys mutation in LRRK2 and analyzed genealogical, clinical, and genetic data from the...

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PMID: 22162019
DOI: 10.1002/mds.24033

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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