Article
Resistance-associated variants in chronic hepatitis C patients treated with protease inhibitors.
Current gastroenterology reports - 1 Feb 2012
Gambarin-Gelwan Maya, Jacobson Ira M
Abstract excerpt
Direct-acting antiviral agents in combination with pegylated interferon (PEG-IFN) and ribavirin (RBV) significantly improve sustained virologic response rate and reduce duration of therapy among both treatment-naïve and treatment-experienced patients with genotype 1 chronic hepatitis C. One of the most important considerations with both boceprevir and telaprevir is the potential development of resistant variants...
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