Article
Importance of HCV genotype 1 subtypes for drug resistance and response to therapy.
Journal of viral hepatitis - 1 Apr 2014
Wyles D L, Gutierrez J A
Abstract excerpt
The treatment for patients infected with hepatitis C virus (HCV) genotype 1 has undergone major changes with the availability of direct-acting antivirals. Triple therapy, containing telaprevir or boceprevir, first-wave NS3 protease inhibitors, in combination with peginterferon and ribavirin, improved rates of sustained virologic response compared with peginterferon and ribavirin alone in patients with HCV...
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