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Article

Resistance to hepatitis C virus protease inhibitors.

Current opinion in virology - 1 Oct 2014

Kieffer Tara L, George Shelley

Abstract excerpt

Significant scientific advances have enabled the development of new classes of antivirals for the treatment of HCV. Protease inhibitors were the first approved, achieving substantially higher response rates, with shorter treatment durations, in the majority of genotype 1 infected patients. However, in patients who fail treatment, drug resistant variants frequently emerge. The pattern of resistant variants...

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Share to Antiviral Agents
Share to Drug Resistance, Viral
Share to Drug Therapy, Combination

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Hepacivirus

Share to Protease Inhibitors

Share to Selection, Genetic

Source

Identifiers

PMID: 24852142
DOI: 10.1016/j.coviro.2014.04.008

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