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Article

S100A7 Enhances Mammary Tumorigenesis through Upregulation of Inflammatory Pathways

13 Dec 2011

Abstract excerpt

S100A7/psoriasin, a member of the epidermal differentiation complex, is widely overexpressed in invasive estrogen receptor (ER)α-negative breast cancers. However, it has not been established whether S100A7 contributes to breast cancer growth or metastasis. Here, we report the consequences of its expression on inflammatory pathways that impact breast cancer growth. Overexpression of human S100A7 or its murine...

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PMID: 22158945
DOI: 10.1158/0008-5472.can-11-0669

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