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Article

NFAT promotes carcinoma invasive migration through glypican-6

30 Aug 2011

Abstract excerpt

Invasive migration of carcinoma cells is a prerequisite for the metastatic dissemination of solid tumours. Numerous mechanisms control the ability of cancer cells to acquire a motile and invasive phenotype, and subsequently degrade and invade the basement membrane. Several genes that are up-regulated in breast carcinoma are responsible for mediating the metastatic cascade. Recent studies have revealed that the...

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PMID: 21871017
DOI: 10.1042/bj20110530

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