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Article

The S100A7-c-Jun activation domain binding protein 1 pathway enhances prosurvival pathways in breast cancer.

Cancer research - 1 Jul 2005

Emberley Ethan D, Niu Yulian, Curtis Linda, Troup Sandra, Mandal Sanat K, Myers Jeffery N, Gibson Spencer B, Murphy Leigh C, Watson Peter H

Abstract excerpt

S100A7 is among the most highly expressed genes in preinvasive breast cancer, is a marker of poor survival when expressed in invasive disease, and promotes breast tumor progression in experimental models. To explore the mechanism of action, we examined the role of S100A7 in cell survival and found that overexpression of S100A7 in MDA-MB-231 cell lines promotes survival under conditions of anchorage-independent...

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PMID: 15994944
DOI: 10.1158/0008-5472.CAN-04-3927

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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