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Article

Activation of NF‐κB by extracellular S100A4: Analysis of signal transduction mechanisms and identification of target genes

11 Jun 2008

Abstract excerpt

The metastasis-promoting protein S100A4 stimulates metastatic progression through both intracellular and extracellular functions. Extracellular activities of S100A4 include stimulation of angiogenesis, regulation of cell death and increased cell motility and invasion, but the exact molecular mechanisms by which extracellular S100A4 exerts these effects are incompletely elucidated. The aim of the present study was...

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PMID: 18548584
DOI: 10.1002/ijc.23617

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