Article
A promoter polymorphism of neurotrophin 3 gene is associated with curve severity and bracing effectiveness in adolescent idiopathic scoliosis.
Spine - 15 Jan 2012
Qiu Yong, Mao Sai-hu, Qian Bang-ping, Jiang Jun, Qiu Xu-sheng, Zhao Qinghua, Liu Zhen
Abstract excerpt
STUDY DESIGN: A genetic association study to comprehensively investigate variations of neurotrophin 3 (NTF3) gene polymorphisms in a Chinese Han population. OBJECTIVE: To explore whether the NTF3 gene polymorphisms are associated with the susceptibility, curve severity, or bracing effectiveness of adolescent idiopathic scoliosis (AIS). SUMMARY OF BACKGROUND DATA: Scoliosis has developed in mice with NTF3...
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