Article
Genetic Variant of SOCS3 Gene is Functionally Associated With Lumbar Adolescent Idiopathic Scoliosis.
Clinical spine surgery - 1 Apr 2018
Qiao Jun, Xiao Lingyan, Xu Leilei, Qian Bangping, Zhu Zezhang, Qiu Yong
Abstract excerpt
STUDY DESIGN: This is a genetic association study. OBJECTIVE: To investigate association between suppressor of cytokine signaling-3 (SOCS3) gene polymorphisms and the onset and progression of lumbar adolescent idiopathic scoliosis (AIS) and to further clarify its role in the regulation of SOCS3 expression in AIS patients. SUMMARY OF BACKGROUND DATA: Some studies showed that muscle development imbalance may be...
Topics
- Adolescent
- Case-Control Studies
- Child
- Gene Expression Regulation
- Gene Frequency
- Genetic Association Studies
- Genetic Predisposition to Disease
- Humans
- Lumbar Vertebrae
- Polymorphism, Single Nucleotide