Predictive value of single-nucleotide polymorphisms in curve progression of adolescent idiopathic scoliosis.

doi:10.1007/s00586-022-07213-y

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Article

Predictive value of single-nucleotide polymorphisms in curve progression of adolescent idiopathic scoliosis.

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society - 1 Sept 2022

Wang Wengang, Chen Tailong, Liu Yibin, Wang Songsong, Yang Ningning, Luo Ming

Abstract excerpt

PURPOSE: Genetic diagnosis is a promising approach because several single-nucleotide polymorphisms (SNPs) associated with adolescent idiopathic scoliosis (AIS) progression have been reported. We review the predictive value of SNPs in curve progression of adolescent idiopathic scoliosis. METHODS: We reviewed DNA-based prognostic testing to predict curve progression. Then, the multiple polymorphisms in loci related...

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PMID: 35434775
DOI: 10.1007/s00586-022-07213-y

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