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Article

A promoter polymorphism of tissue inhibitor of metalloproteinase-2 gene is associated with severity of thoracic adolescent idiopathic scoliosis.

Spine - 1 Jan 2012

Jiang Jun, Qian Bangping, Mao Saihu, Zhao Qinghua, Qiu Xusheng, Liu Zhen, Qiu Yong

Abstract excerpt

STUDY DESIGN: A genetic association study of the tissue inhibitor of metalloproteinase-2 (TIMP-2) gene with adolescent idiopathic scoliosis (AIS) in a Chinese population. OBJECTIVE: To determine whether a promoter polymorphism of the TIMP-2 gene correlates with the occurrence and curve severity of AIS patients. SUMMARY OF BACKGROUND DATA: Previous studies have suggested that genetic factors play an important role...

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Identifiers

PMID: 21228746
DOI: 10.1097/BRS.0b013e31820e71e3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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