[Effect of genetic polymorphism of MTNR1A gene on adolescent idiopathic scoliosis].

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[Effect of genetic polymorphism of MTNR1A gene on adolescent idiopathic scoliosis].

Zhonghua wai ke za zhi [Chinese journal of surgery] - 15 Sept 2007

Qiu Xu-sheng, Tang Leung-sang, Yeung Hiu-yan, Kwok Hoi-kei, Lee Kwong-man, Qin Ling, Qiu Yong, Cheng Chun-yiu

Abstract excerpt

OBJECTIVE: To investigate whether the MTNR1A gene promotor polymorphism (rs2119882) are associated with the occurrence or curve severity of adolescent idiopathic scoliosis (AIS). METHODS: 226 AIS patients and 277 normal controls were recruited. The maximum Cobb angles were recorded in AIS patients. PCR-RFLP was used for the genotyping. RESULTS: The genotype and allele frequency distribution were comparable...

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PMID: 18067741

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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