A Genetic Variant of the ROBO3 Gene is Associated With Adolescent Idiopathic Scoliosis in the Chinese Population.

doi:10.1097/BRS.0000000000004484

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Article

A Genetic Variant of the ROBO3 Gene is Associated With Adolescent Idiopathic Scoliosis in the Chinese Population.

Spine - 15 Jan 2023

Zhang Zheng, Zhang Zhanrong, Shu Lun, Meng Yichen, Ma Jun, Gao Rui, Zhou Xuhui

Abstract excerpt

STUDY DESIGN: A case-control association study. OBJECTIVES: This study aimed to reveal whether mutations within roundabout receptor 3 ( ROBO3 ) gene were related to adolescent idiopathic scoliosis (AIS) in Chinese Han population and to investigate the functional role of ROBO3 in the pathogenesis and progression of AIS. SUMMARY OF BACKGROUND DATA: ROBO3 is essential for the regulation of hindbrain axonal cell...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 36149840
DOI: 10.1097/BRS.0000000000004484

Genes

ROBO3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.