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Article

Detection of EGFR mutation status in lung adenocarcinoma specimens with different proportions of tumor cells using two methods of differential sensitivity.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Feb 2012

Han Hye-Suk, Lim Sung-nam, An Jin Young, Lee Ki Man, Choe Kang Hyeon, Lee Ki Hyeong, Kim Seung Taik, Son Seung-Myoung, Choi Song-Yi, Lee Ho-chang, Lee Ok-Jun

Abstract excerpt

INTRODUCTION: To evaluate epidermal growth factor receptor (EGFR) mutation status in lung adenocarcinoma specimens with different proportions of tumor cells using two methods with different sensitivities. METHODS: EGFR mutation status was determined by peptide nucleic acid (PNA) clamping and direct sequencing. The samples consisted of 41 cell blocks of malignant pleural effusions with various proportions of tumor...

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Share to Adenocarcinoma
Share to Carcinoma, Non-Small-Cell Lung

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Neoplasm

Share to ErbB Receptors

Share to Peptide Nucleic Acids

Share to Pleural Effusion, Malignant

Share to Sensitivity and Specificity

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 22157369
DOI: 10.1097/JTO.0b013e31823c4c1b

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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