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Article

Effective assessment of egfr mutation status in bronchoalveolar lavage and pleural fluids by next-generation sequencing.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Feb 2013

Buttitta Fiamma, Felicioni Lara, Del Grammastro Maela, Filice Giampaolo, Di Lorito Alessia, Malatesta Sara, Viola Patrizia, Centi Irene, D'Antuono Tommaso, Zappacosta Roberta, Rosini Sandra, Cuccurullo Franco, Marchetti Antonio

Abstract excerpt

PURPOSE: The therapeutic choice for patients with lung adenocarcinoma depends on the presence of EGF receptor (EGFR) mutations. In many cases, only cytologic samples are available for molecular diagnosis. Bronchoalveolar lavage (BAL) and pleural fluid, which represent a considerable proportion of cytologic specimens, cannot always be used for molecular testing because of low rate of tumor cells. EXPERIMENTAL...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23243218
DOI: 10.1158/1078-0432.CCR-12-1958

Genes

EGFR
EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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