Article
Assessment of EGFR mutation status using cell-free DNA from bronchoalveolar lavage fluid.
Clinical chemistry and laboratory medicine - 28 Aug 2017
Park Sojung, Hur Jae Young, Lee Kye Young, Lee Jae Cheol, Rho Jin Kyung, Shin Sun Hwa, Choi Chang-Min
Abstract excerpt
BACKGROUND: Much attention has been focused on epidermal growth factor receptor (EGFR) mutation testing since the introduction of EGFR-tyrosine kinase inhibitors have improved survival in EGFR-positive lung cancer patients. Liquid biopsy using circulating tumor cells or cell-free DNA (cfDNA) has enabled less invasive testing, but requires a highly sensitive method. To date, liquid biopsy using bronchoalveolar...
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