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Article

Peptide Nucleic Acid Clamping and Direct Sequencing in the Detection of Oncogenic Alterations in Lung Cancer: Systematic Review and Meta-Analysis.

Yonsei medical journal - 1 Mar 2018

Song Jae Uk, Lee Jonghoo

Abstract excerpt

PURPOSE: Molecular testing in non-small cell lung cancer (NSCLC) aids in identifying oncogenic alterations. The aim of this study was to compare the rates of detection of oncogenic alterations and responsiveness to epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) according to EGFR mutation status as determined by peptide nucleic acid (PNA) clamping or direct sequencing (DS). MATERIALS AND...

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Share to Carcinoma, Non-Small-Cell Lung
Share to Molecular Diagnostic Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Peptide Nucleic Acids

Share to Protein Kinase Inhibitors

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Share to Translocation, Genetic

Source

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Identifiers

PMID: 29436188
DOI: 10.3349/ymj.2018.59.2.211
PMCID: PMC5823822

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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